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Cyproterone Acetate + Ethinylestradiol

Drug Class: Commonly Known As: Category:
Contraceptive Estelle-35/35 ED Adult

Cyproterone Acetate + Ethinylestradiol - Dosage and How to Use

How should Cyproterone Acetate + Ethinylestradiol be used?

  • Do not stop taking your medication without checking with your healthcare professional.
  • You should take this medication after food.
  • You may start taking this medication on the first or second day of your menses (if this is your first time taking hormonal contraceptives or restarting this medication after a break).
  • If you are also using it for contraceptive purposes, a barrier method of contraception e.g. condoms, is recommended for the first 7 days of taking Estelle™-35/35 ED for the first time.
  • You should take one yellow (active) tablet daily for 21 consecutive days, preferably at the same time every day. Each subsequent pack is started after a 7-day tablet-free interval or 7-day period of white (inactive) tablets, during which a withdrawal bleeding (menses) usually occurs. This usually starts on day 2-3 after the last yellow (active) tablet is taken. 
  • Start taking your next pack of medication after the 7-day tablet-free days or 7-day period of white (inactive) tablets, even if you are still having menstrual bleeding.

What should I do if I miss a dose?

There is no action needed if you have missed the white (inactive tablets) ; however you must  follow the steps below if you miss any of your 21 yellow (active) tablets to ensure that contraception effect is not reduced.

Within 12 hours:
Take the missed tablet as soon as remembered. Take the next tablet at your usual time.

More than 12 hours:
If the missed tablet is within

  • Week 1 of the pack: 
    • Take the missed tablet as soon as remembered, even if it means taking 2 tablets at the same time.
    • Continue to take your tablets at your usual time on the next day.
    • Use a barrier method such as a condom for the next 7 days.
If sexual intercourse happened in the previous 7 days, you may be pregnant. See your doctor for advice as soon as possible.
  • Week 2 of the pack: 
    • Take the missed tablet as soon as remembered, even if it means taking 2 tablets at the same time.
    • Continue to take your tablets at your usual time on the next day. 
    • If you have taken your tablets correctly in the 7 days before the first missed tablet, there is no need to use extra contraceptive precautions. However if this is not the case, or you have missed more than 1 tablet, use a barrier method such as a condom for the next 7 days.
  • Week 3 of the pack:  Depending on whether you have taken your tablets correctly in the 7 days before the first missed tablet, you would have to follow the following options:
​No missed tablets in the last 7 days

​Take the missed tablet as soon as remembered, even if it means taking 2 tablets at the same time. 

Continue to take your tablets at your usual time and start the next pack right away without the 7-day tablet free period or 7-day white (inactive) tablets i.e. no gap should be left between packs. Your menses may not come until the next pack is finished, but there is no need to worry. However, if your menses do not occur after the next pack is finished, you should take a pregnancy test to make sure you are not pregnant.

OR

Stop taking medication from the current pack for 7 days (7-day tablet-free period). A withdrawal bleed (menses) usually occurs and then start a next pack after 7 days.

​Missed tablet in the last 7 days

​Take the missed tablet as soon as remembered, even if it means taking 2 tablets at the same time. 

Continue to take your tablets at your usual time and start the next pack right away without the 7-day tablet free period or 7-day white (inactive) tablets i.e. no gap should be left between packs. Your menses may not come until the next pack is finished, but there is no need to worry. However, if your menses does not occur after the next pack is finished, you should take a pregnancy test to make sure you are not pregnant.

AND
Use a barrier method such as a condom for the next 7 days

 

**If you miss your period (especially with missed tablets), check with your doctor to determine if you are pregnant before continuing to take the next cycle of contraceptives.

If you vomit or suffer from diarrhea within 3 to 4 hours of taking this medication, the tablet may not be absorbed. This is considered a missed dose. You should then follow the instructions above.

What should I do if I overdose?

Cyproterone Acetate + Ethinylestradiol - Additional Information

  • Updated on 3/31/2023 12:00:00 AM
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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