Skip Ribbon Commands
Skip to main content


Drug Class: Commonly Known As: Category:

Colchicine - Side Effects, Precautions, and Contraindications

What side effects can Colchicine cause?

Side effects may occur when taking Colchicine, but the majority of these effects tend to resolve spontaneously. Common side effects include:

  • Nausea, vomiting, abdominal cramp and diarrhoea. These may be reduced by taking Colchicine with food. If you experience severe vomiting, abdominal cramp or diarrhoea during treatment for a flare, you should stop taking the medicine.
  • Loss of appetite

The chance of side effects is lower when lower dose is used for prevention purpose.

Consult your doctor or pharmacist about any symptoms that becomes bothersome.

Before taking Colchicine, what precautions must I follow?

Colchicine may interact with other medicine or supplement that you are taking.

Inform the doctor, pharmacist or specialty nurse before starting any medicines and supplements. Your doctor may reduce your Colchicine dose when taken with medicines such as statins (a class of cholesterol lowering medicines), as they might increase the chance of you experiencing severe side effects.

What food or medicine must I avoid when I take Colchicine?

  • Updated on Friday, June 12, 2015
  • Article contributed by Department of Pharmacy, Rheumatology & Immunology Singapore General Hospital

    Find Your Medicines