In most patients, symptoms and functional impairment can be managed effectively and normal life expectancy is expected unless there is a co-existent systemic disease.
One should adopt a healthy lifestyle so as to encourage nerve regeneration. Active and passive forms of exercise can improve muscle strength and prevent muscle wasting in paralysed limbs.
Meticulous foot care is also important, especially in diabetic polyneuropathy. Mechanical aids can help to reduce pain and improve function. Hand or foot braces can compensate for muscle weakness or alleviate nerve compression.