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Fever of Unknown Origin / Pyrexia of unknown origin

Fever of Unknown Origin / Pyrexia of unknown origin - How to prevent?

Fever of Unknown Origin / Pyrexia of unknown origin - Causes and Risk Factors

There are many causes of FUO / PUO, ranging from infections to autoimmune diseases to malignancies.  Some common causes of FUO / PUO include the following:
  • Infections such as tuberculosis, human immunodeficiency virus infection, infective endocarditis, undrained abscesses and viral infections.
  • Autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, temporal arteritis, polymyalgia rheumatica, mixed connective tissue disorders, adult onset Still’s disease, etc.
  • Hematological malignancies such as lymphoma and leukemia. 
  • Solid organ malignancies such as hepatocellular carcinoma and renal cell carcinoma.
  • Miscellaneous conditions including drug fever, hypersensitivity syndrome and Kikuchi’s disease 
Unfortunately, in 10-20% of cases, the cause of the FUO / PUO remain undiagnosed.

Fever of Unknown Origin / Pyrexia of unknown origin - Preparing for surgery

Fever of Unknown Origin / Pyrexia of unknown origin - Post-surgery care

Fever of Unknown Origin / Pyrexia of unknown origin - Other Information

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