There are no known ways to prevent most bile duct cancers. Many of the known risk factors for bile duct cancer, such as age, ethnicity, genetics and bile duct abnormalities are beyond our control. Nonetheless, there are some things you can do that might lower your risk.
You can lower your risk for developing CCA by leading a healthy lifestyle, such as regular exercise, controlling your weight, and eating a healthy balanced diet.
It's also important to avoid infection with the hepatitis B and C viruses. Hepatitis B and/or C infection may increase the risk of developing CCA and it can lead to liver scarring (cirrhosis), liver failure and liver primary cancer. There is no vaccine for hepatitis C currently but the right treatment may control or eliminate the virus. If you have chronic hepatitis, you should visit your doctors for regular surveillance with imaging tests, such as ultrasound.
Quit (or don't start) smoking and avoid excessive alcohol consumption.
Avoid exposure to known cancer-causing (carcinogenic) chemicals