You are invited to the upcoming seminar:
Presenter:
Prof Liu Yan
Professor in Neuroscience
Institute for Stem Cell and Neural Regeneration
Nanjing Medical University
Title: Premature neural differentiation regulated by FABP7 in organoids derived from autism individuals
Abstract:
The diverse clinical phenotypes of ASD have hampered the elucidation of pathological mechanisms. Based on iPSCs-derived cerebral organoids from ASD individuals, multiple cell lines and time series scRNA-seq combined with histomorphological analysis showed premature neural differentiation of neural stem cells and decreased expression of Fatty acid binding protein 7 (FABP7) in the ASD organoids. Meanwhile, upregulation of FABP7 rescued improper neural differentiation in the ASD organoids.
Seminar Details:
Date: 4 October 2023, Wednesday
Time: 2:30pm to 3:30pm
Venue:
Room 7C, Level 7, Duke-NUS
Host:
Asst Prof Alfred Sun
Principal Investigator
Neuroscience & Behavioural Disorders Programme
Duke-NUS
All are welcome. No registration is required.