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Dr Aw Swee Eng

Senior Consultant, Director, Endocrine Laboratories

Department of Nuclear Medicine and PET

MBBS, PhD (Chem Path)(Lond), FRCPath (Lond), FAMS

Dr. Aw Swee Eng (MBBS, PhD, MRC Path, MI Biol, FRC Path) is a Senior Consultant and a past Head of the Department of Nuclear Medicine and PET at SGH. He was the Director, Department of Clinical Research and past Chairman, SGH Office of Biomedical Ethics. His current interests include the field of diagnostics and anticancer drugs.

 

PROFESSIONAL APPOINTMENTS & COMMITTEE MEMBERSHIPS

  • Chairman, Department of Clinical Research Committee, 1.6.00 – June 09
  • Committee Member, MOH Committee to Develop the Code of Ethical Practice in Human Biomedical Research, 24 Apr 08 - 23 Apr 09.
  • Chairman, SGH Institutional Review Board (IRB), 1Jan 09 – 31 Dec 10.
  • Chairman, SingHealth Centralized Institutional Review Board, 16 Feb 09 – present
  • Clinician Mentor 11 May 2009
  • Committee Member, SGH Institutional Biosafety Committee (IBC), 1 Jul 07 – present

AWARDS

  • 1984 ( National Day ) Public Administration Silver Medal ( PPA )

PUBLICATIONS AND RESEARCH/TRIALS

  • Study of gene expression profile during cord blood-associated megakaryopoiesis. Lim Che Kang, William Hwang YK, Aw Swee Eng, Sun Li. Eur J Haematology 2008 Apr: 81(3); 196-208..
  • Biological characteristics of megakaryocytes : Specific lineage commitment and associated disorders. Sun L, Hwang WEK, Aw SE. International J of Biochem Cell Biol 38(11), 821-826, 2006 Apr 3.
  • Gene regulation profile reveals consistent anti-cancer properties of progesterone in hormone-independent breast cancer cells transfected with progesterone receptor. Joyce CL Leo, Suk Mei Wang, Chun Hua Guo, Swee Eng Aw, Yi Zhao, Jin Ming Li, Kam M. Hui and Valerie CL Lin International Journal of Cancer 117, 561-68, 2005.
  • A novel anti-estrogenic mechanism in progesterone receptor-transfected breast cancer cells. Ze-Yi Zheng, Boon-Huat Bay, Swee-Eng Aw, and Valerie C-L Lin. J. Biological Chemistry 280(17) 17480-87, 29 Apr 2005.
  • Cloning and identification of hepatocellular carcinoma down-regulated mitochondrial carrier protein, a novel liver-specific uncoupling protein. Michelle Tan Guet Khim, Ooi LL, Aw Swee Eng, Hui KM. J Biol Chem 279(43) : 45235-44, Oct 2004.
  • Glucocorticoid and Mineralocorticoid Cross-Talk with Progesterone Receptor to Induce Focal Adhesion and Growth Inhibition in Breast Cancer Cells. Joyce CL Leo, C Guo, CT Woon, SE Aw, Valerie CL Lin. Endocrinology 145(3):1314-21, 2004.
  • Distinct molecular pathways mediate progresterone-induced growth inhibition and focal adhesion. Lin VC, Woon CT, Aw SE, Guo C. Endocrinology 144(12):5650-7, December 2003. Epub 2003 Sep 11.
  • Progesterone induces cellular differentiation in MDA-MB-231 breast cancer cells transfected with progesterone receptor complementary DNA. Lin VC, Jin R, Tan PH, Aw SE, Woon CT, Bay BH. Am J Pathol. 162(6): 1781-7, June 2003.

Last Modified Date :04 Jan 2010