Research in the department focuses mainly on clinical studies, with the overall aims of improving clinical care and management of patients. This can be broadly divided into 3 main categories – Oncologic Imaging, Radionuclide Therapy and Basic Science. Some of the main areas of research as listed below:
Oncologic Imaging
(1) Gallium-68 DOTA-TATE and analogues for imaging of neuroendocrine and other tumours.
(2) [F-18] FDG PET/CT imaging for lymphomas, hepatocellular carcinoma.
(3) [F-18] Choline PET/CT imaging for brain and prostate tumours.
(4) SPECT/CT imaging for musculoskeletal disorders.
General Nuclear Medicine and therapeutic Nuclear Medicine
- Intra-arterial therapy for hepatocellular carcinoma, using Yttrium-90 microspheres.
- Radiosynovectomy for chronic arthritis using phosphorus-32.
- Alpha-emitter radium-223 bone metastatic disease.
- Implantable 32P BioSiliconTM, administered intratumourally to patients with advanced, unresectable pancreatic cancer, in addition to standard intravenous gemcitabine chemotherapy.
- Thyroid carcinoma – treatment and diagnosis.
Basic Science
- Radiolabelled amino-acids and peptides.
- Gallium-68 radiochemistry
For more information, please contact secretary, Department of Nuclear Medicine and PET, Singapore General Hospital.