RESEARCH ACTIVITIES
1. Head and Neck Surgery
- Surgery and adjuvant radiotherapy versus concurrent chemo-radiotherapy for resectable stage III and IV head and neck squamous cell carcinoma. NMRC grant obtained.
- Photodynamic therapy in management of Nasopharyngeal carcinoma.
- Genetic Studies in Head and Neck Cancer - the association of the H19 gene with nasopharyngeal cancer.
- Nasopharyngeal carcinoma: Radiotherapy versus concurrent chemo-radiation therapy in treatment for advanced staged disease.
- Nasopharyngeal carcinoma: Study early detection and development of a vaccine.
2. Otology
- Effect of radiation on the ear.
Investigate radiation-induced apoptosis in inner ear hair-cells and middle ear effusion.
- Cochlear Implantation in Children and Adults.
Investigate factors contributing to the success of cochlear implantation.
- Childhood Hearing Screening and Intervention.
Investigate universal newborn hearing screening and the results of early intervention.
- Racial differences in the practice of Otology.
Study the impact of racial anatomical and physiological differences on the practice of Otology.
- Genetic aspects of childhood hearing loss.
Study pheynotypic and genotypic correlations of hereditary non-syndromic hearing loss in Singapore.
3. Laryngology and Voice
- Efficacy of percutaneous hyaluronic-acid injection to improve voice and swallowing in patients with unilateral vocal-fold paralysis.
- Anatomy of the South East Asian larynx related to vocal fold medialisation procedures to treat unilateral vocal fold paralysis.
- Near infrared atuofluorescence and Raman spectroscopy for head and neck diagnosis.
- Role of electrical stinulation (e-stim) in treating swallowing disorders. Multi-centre trial.
- Lateralisation of motor cortex excitability in vocalisation and muscial tasks.
- Effectiveness of gatric acid suppression therapy in treatment of laryngeal pathology.
- Prevalence of voice disorders in occupational voice users in Singapore.
- Laryngeal electromyography in patients with vocal fold paralysis following head and neck radiotherapy.
4. Rhinology
- Role of endoscopic ligation of sphenopalatine artery in the management of epistaxis.
- Endoscopic sinusotomy in the management of frontal sinus disease.
- Multimedia Book on Endoscopic Sinus Surgery.
- Nasal Obstruction and Smell. Study effect of nasal obstruction on Eustachian tube dysfunction, snoring and headaches. Development of a new olfactometer.z
- Three-dimensional CT angiography (3DCTA) of the internal carotid artery for preoperative evaluation of sinonasal lesions and intraoperative surgical navigation: to assess the role of 3DCTA, when combined with intraoperative surgical navigation, in the applications of minimally invasive endoscopic approaches to the skull base.
- Evaluation of skull base lesions with CT and MR image fusion for preoperative planning and intraoperative endoscopic surgical navigation: to assess the role of CT-MRI image fusion studies for diagnostic evaluation and/or preoperative planning during intraoperative endoscopic surgical navigation.
5. Snoring & Obstructive Sleep Apnea
- The effects of radiofrequency treatment of the palate on snoring : a prospective study.
- The effects of radiofrequency treatment of the nasal turbinates on nasal congestion.
- Morphological assessment of snorers and non-snores : a comparative study.
6. Paediatric Otolaryngology
- Analysis of more than one thousand skin prick allergen tests in children.
- Endoscopic Transnasal correction of Choanal Atresia.
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